Rabbit
WB
Human, Mouse,Rat
WB 1:500-2000
-20°C/1 year
This antibody detects endogenous levels of FBXW5 at Human/Mouse/Rat
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Synthesized peptide derived from human FBXW5
Q969U6
F-box/WD repeat-containing protein 5 (F-box and WD-40 domain-containing protein 5)
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.132% sodium azide.
Polyclonal
IgG
This gene encodes a member of the F-box protein family, members of which are characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into three classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene contains WD-40 domains, in addition to an F-box motif, so it belongs to the Fbw class. Alternatively spliced transcript variants encoding distinct isoforms have been identified for this gene, however, they were found to be nonsense-mediated mRNA decay (NMD) candidates, hence not represented. [provided by RefSeq, Jul 2008],
FBXW5 FBW5 PP3971, FBXW5
1 mg/ml
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