PKAα cat (phospho Ser338) rabbit pAb

Cat :A19888

PKA,A19888, 19888, PRKACA, cAMP-dependent protein kinase catalytic subunit alpha, PRKACA; PKACA; cAMP-dependent protein kinase catalytic subunit alpha; PKA C-alpha

Price： ¥900¥1600

Size： 50ul 100ul

Datasheet

MSDS

Source

Rabbit
Applications

IHC,ELISA
Reactivity

Human,Mouse,Rat
Dilution

IHC: 1:100 - 1:300. ELISA: 1:5000. Not yet tested in other applications.
Storage

-20°C/1 year
Specificity

Phospho-PKAα cat (S338) Polyclonal Antibody detects endogenous levels of PKAα cat protein only when phosphorylated at S338.
Source/Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Immunogen

Synthesized phospho-peptide around the phosphorylation site of human PKAα cat (phospho Ser338)
Uniprot No

P17612
Alternative names

PRKACA; PKACA; cAMP-dependent protein kinase catalytic subunit alpha; PKA C-alpha
Form

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Clonality

Polyclonal
Isotype

IgG
Background

protein kinase cAMP-activated catalytic subunit alpha(PRKACA) Homo sapiens This gene encodes one of the catalytic subunits of protein kinase A, which exists as a tetrameric holoenzyme with two regulatory subunits and two catalytic subunits, in its inactive form. cAMP causes the dissociation of the inactive holoenzyme into a dimer of regulatory subunits bound to four cAMP and two free monomeric catalytic subunits. Four different regulatory subunits and three catalytic subunits have been identified in humans. cAMP-dependent phosphorylation of proteins by protein kinase A is important to many cellular processes, including differentiation, proliferation, and apoptosis. Constitutive activation of this gene caused either by somatic mutations, or genomic duplications of regions that include this gene, have been associated with hyperplasias and adenomas of the adrenal cortex and are linked to corticotropin-independent Cushing's syndrome. Altern
Other

PRKACA, cAMP-dependent protein kinase catalytic subunit alpha
Mol.Wt (Da)

40590
Concentration

1 mg/ml