Siglec-5/14 rabbit pAb

Cat :A21540

Siglec,A21540, 21540, SIGLEC5/SIGLEC14, Sialic acid-binding Ig-like lectin 5/Sialic acid-binding Ig-like lectin 14, SIGLEC5; CD33L2; OBBP2; Sialic acid-binding Ig-like lectin 5; Siglec-5; CD33 antigen-like 2; Obesity-binding protein 2; OB-BP2; OB-binding

Price： ¥900¥1600

Size： 50ul 100ul

Datasheet

MSDS

Source

Rabbit
Applications

WB,IHC,ELISA
Reactivity

Human
Dilution

WB: 1:500 - 1:2000. IHC: 1:100-300 ELISA: 1:20000. Not yet tested in other applications.
Storage

-20°C/1 year
Specificity

Siglec-5/14 Polyclonal Antibody detects endogenous levels of Siglec-5/14 protein.
Source/Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Immunogen

Synthesized peptide derived from Sialic acid-binding Ig-like lectin 5/Sialic acid-binding Ig-like lectin 14 at AA range: 91-140
Uniprot No

O15389
Alternative names

SIGLEC5; CD33L2; OBBP2; Sialic acid-binding Ig-like lectin 5; Siglec-5; CD33 antigen-like 2; Obesity-binding protein 2; OB-BP2; OB-binding protein 2; CD170; SIGLEC14; Sialic acid-binding Ig-like lectin 14; Siglec-14
Form

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Clonality

Polyclonal
Isotype

IgG
Background

sialic acid binding Ig like lectin 5(SIGLEC5) Homo sapiens This gene encodes a member of the sialic acid-binding immunoglobulin-like lectin (Siglec) family. These cell surface lectins are characterized by structural motifs in the immunoglobulin (Ig)-like domains and sialic acid recognition sites in the first Ig V set domain. The encoded protein is a member of the CD33-related subset of Siglecs and inhibits the activation of several cell types including monocytes, macrophages and neutrophils. Binding of group B Streptococcus (GBS) to the encoded protein plays a role in GBS immune evasion. [provided by RefSeq, Feb 2012],
Other

SIGLEC5/SIGLEC14, Sialic acid-binding Ig-like lectin 5/Sialic acid-binding Ig-like lectin 14
Mol.Wt (Da)

60715/43970
Concentration

1 mg/ml